凡德不可治疗肺癌

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本帖最后由李满玉于 2015-12-16 23:05 编辑

1. http://www.ncbi.nlm.nih.gov/pubmed/22370318
这片文章显示凡德不仅无用, 副作用还大, 不可用与治疗肺癌.
CONCLUSION:
The study did not demonstrate an overall survival benefit for vandetanib versus placebo. There was a higher incidence of some adverse events with vandetanib.
2. https://en.wikipedia.org/wiki/Vandetanib
Clinical trials[edit]
Non-small cell lung cancer[edit]
The drug underwent clinical trials as a potential targeted treatment for non-small-cell lung cancer. There have been some promising results from a phase III trial with docetaxel.[12] There have also been ambivalent results when used with pemetrexed.[13] Another trial with docetaxel was recruiting in July 2009.[14]
AstraZeneca withdrew EU regulatory submissions for vandetanib (under the proposed trade name Zactima) in October 2009 after trials showed no benefit when the drug was administered alongside chemotherapy.[15]
阿斯利康已经于2009 年十月撤消了临床试验. 它和安慰剂没有任何治疗的统计差异,也就是无任何作用, 除了一些副作用. 因此大家应该慎重考虑. 我观察到网友也基本是无作用或作用不大的反应.

sunzongbao2007 · 发表于 2015-12-18 08:50:26

恩？那就是不用准备凡德他尼了么？

pingpinger21 · 发表于 2015-12-19 15:39:16

我看好多病友都吃过

18952090760 · 发表于 2015-12-20 15:27:25

我吃的，反应很大，吃2片降压药血压都下不来，赶紧停药

sqxyz · 发表于 2015-12-20 16:31:11

论坛里有部分人吃了是有效的呀，抑制E靶点和V靶点

春野 · 发表于 2015-12-20 20:56:09

我曾服凡德24天，副作用很大，CT肺部进展，停服

李满玉 · 发表于 2015-12-21 20:41:41

个人觉得还是应该相信用凡德做过临床试验的药厂, 有用的话为什么不继续? 病友有反映有效的, 但是进一步看用凡德期间CEA基本无降低, 或无明显降低.

LOVEME · 发表于 2015-12-21 21:58:50

谢谢分享信息！

APPLE · 发表于 2015-12-21 22:32:09

获得最新信息，感谢楼主！

Yunxiao · 发表于 2015-12-23 06:43:35

我家刚吃上特，想着按憨叔的方法，下一步要换凡德呢，现在这样，我该换什么呢？好纠结