孤啸 发表于 2011-7-18 12:43
是不是以前做过放疗的也要慎用阿瓦呢?谢谢。
By Dr. West
"There isn't a clear contraindication based on location or prior radiation, but that doesn't mean it's proven to be totally safe. Many lung cancer specialists and some general oncologists have become increasingly wary about combining significant chest radiation with Avastin (bevacizumab), especially concurrently but even possibly sequentially, due to an observation of more tracheoesophageal fistulas. I would be doubly wary in someone who had received more than a standard amount of radiation to the chest. "
(我尽量翻译的通顺一些)
对放射部位或已做过放射的病人,没有明确的禁忌说不能再使用其他的药,但这并不证明是完全安全。许多肺癌专家和一些肺癌医生越来越谨慎一定剂量的胸部放射和阿瓦的联合使用,特别是同时使用,甚至对前后相继使用,原因是观察到更多的tracheoesophageal fistulas案例。我本人对过剂量胸放射的病人会加倍谨慎。
|